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Innovative therapy platforms and biomimetics for personalized medicine and targeted drug development

Published: November 2025

Personalized drug development utilizes RNA-based therapeutics, gene therapy, and CRISPR delivery to tailor disease treatments. Biomimetic and nano-based systems enhance drug delivery through nanocarriers, microneedle patches, and theranostic systems, while advances in cancer therapy, organ- and cell-based therapeutics, and diagnostic imaging and monitoring open new avenues for precise and efficient therapies. This requires comprehensive pre-testing and individualized patient characterization. Achieving medical success depends on high-resolution analytics and advances in biotechnological and chemical research (novel developments in drug discovery, point-of-care diagnostics, etc.).

Guiding questions

  • What technological breakthroughs are needed to fully exploit biomimetic approaches in personalized medicine?
  • How can advanced technologies (e.g., CRISPR, 3D bioprinting) be integrated into existing medical infrastructures?
  • How can the economic benefits of personalized and biomimetic medicine be realized?
  • What investments are necessary to ensure global competitiveness? Which actors (public vs. private) should bear these costs?
Image description: A group of people in lab coats are working on a holographic screen.

challenges

While research – particularly since the complete sequencing of the human genome – is making great strides, sustainable solutions for clinical practice are lacking in the field of personalized medicine. Marketable product innovations are needed because scalability is limited, and the development and production of personalized drugs and therapies are not only costly but also highly demanding. This high level of complexity also stems from the fact that expertise from biotechnology, nanotechnology, and materials science must be incorporated, requiring interdisciplinary research and development.

Concrete examples

  • 3D-printed organs, tissues and implants (biocompatible materials)
  • Nanobots for drug delivery and time-controlled release
  • Organoids for drug testing
  • Cell therapies (CAR-T cells)
  • Biomimetic support structures
  • Biomimetic neuroprostheses
Image description: Foresight – Thuringia, Blue Eye in focus

Foresight Report

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Reference

Your contact persons

Reference

Michel Reichardt

Michel Reichardt Project Manager Strategic Foresight

Christoph Grollman

Christoph Grollman Project Manager Strategic Foresight

Dr. Sophia Gänßle

Dr. Sophia Gänßle Project Manager Data Science Strategic Foresight

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