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Biotechnological innovations and genomics to improve quality of life

Published: November 2025

In modern biotechnology, particularly genomics, significant progress has been made in recent years. These advances can contribute to improving quality of life by utilizing advanced gene editing, molecular diagnostic tools, and nanotechnology to develop new treatment methods and preventive approaches. Genome-editing technologies (CRISPR/Cas9, Prime Editing) enable precise changes to the genetic material, which is promising for gene therapy applications as well as plant and animal breeding, and precision medicine allows therapies to be tailored exactly to individual genetic profiles. Through the exploration of genetic mechanisms, the use of big data, and the integration of innovative medical sensors, these technologies aim to better detect and treat diseases and promote overall health.

Guiding questions

  • Which biotechnological innovations and genome-editing technologies will have the greatest impact on human health and quality of life?
  • What regulatory frameworks are required to ensure the safe use of genome-editing technologies and prevent misuse?
  • How can biotechnological developments be used to solve global environmental problems, such as reducing pesticides or developing climate-resistant plants?
Image description: Two people in lab coats standing next to a DNA structure.

Challenges

Precise interventions in human and animal DNA are complex, as even minimal errors can have unpredictable health or ecological consequences. To safely apply CRISPR technology, it is essential to minimize off-target effects (unintended genetic changes at incorrect locations). This requires further research into molecular mechanisms and tools for detecting such effects. Another challenge is that changes to the human germline also affect future generations and could have irreversible effects. In addition to technical research, the inclusion of social science is therefore necessary to develop ethical guidelines and communicate the risks and benefits.

Concrete examples

  • Gene-based therapies for genetic diseases (cystic fibrosis, sickle cell anemia, or Huntington's)
  • Early detection through genome analysis (Alzheimer's, diabetes, cardiovascular diseases)
  • Bioprinting of organs
Bildbeschreibung / description: Foresight – Thuringia, Blue Eye in Focus

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Michel Reichardt

Michel Reichardt Project Manager Strategic Foresight

Christoph Grollman

Christoph Grollman Project Manager Strategic Foresight

Dr. Sophia Gänßle

Dr. Sophia Gänßle Project Manager Data Science Strategic Foresight

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