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Biotechnological innovations and genomics to improve quality of life

Published: November 2025

Significant progress has been made in modern biotechnology, particularly in genomics, in recent years. This progress can contribute to improving quality of life by utilizing advanced gene editing, molecular diagnostic tools, and nanotechnology to develop new treatments and preventative approaches. Genome-editing technologies (CRISPR/Cas9, prime editing) enable precise modifications to the genome, which holds great promise for gene therapy applications as well as plant and animal breeding. Precision medicine allows therapies to be tailored precisely to individual genetic profiles. By exploring genetic mechanisms, utilizing big data, and integrating innovative medical sensors, these technologies aim to better detect and treat diseases and promote overall health.

Guiding questions

  • Which biotechnological innovations and genome-editing technologies will have the greatest impact on human health and quality of life?
  • What regulatory frameworks are needed to ensure the safe use of genome-editing technologies and to prevent misuse?
  • How can biotechnological developments be used to solve global environmental problems, such as reducing pesticides or developing climate-resistant plants?
Image description: Two people in lab coats are standing next to a DNA structure.

challenges

Precise interventions in human and animal DNA are complex, as even minimal errors can have unpredictable health or environmental consequences. To ensure the safe application of CRISPR technology, it is essential to minimize off-target effects (unintended gene modifications in the wrong locations). This requires further research into molecular mechanisms and tools for detecting such effects. Another challenge is that changes in the human germline can affect future generations and may have irreversible effects. Therefore, in addition to technical research, the involvement of social science is necessary to develop ethical guidelines and communicate the risks and benefits.

Concrete examples

  • Gene-based therapies for genetic diseases (cystic fibrosis, sickle cell anemia or Huntington's disease)
  • Early detection through genome analysis (Alzheimer's, diabetes, cardiovascular diseases)
  • Bioprinting of organs
Image description: Foresight – Thuringia, Blue Eye in focus

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Reference

Your contact persons

Reference

Michel Reichardt

Michel Reichardt Project Manager Strategic Foresight

Christoph Grollman

Christoph Grollman Project Manager Strategic Foresight

Dr. Sophia Gänßle

Dr. Sophia Gänßle Project Manager Data Science Strategic Foresight

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